Combination mRNA cancer vaccine and Keytruda sustains recurrence-free survival at five years
Metastatic melanoma cells – Image Credit National Cancer Institute CANCER DIGEST – Jan. 24, 2026 – When a personalized mRNA cancer vaccine is added to an immunotherapy for the treatment of advanced melanoma, more patients survived without recurrence than those treated with pembrolizumab (Keytruda®) alone, the five-year updated results of a clinical trial show. The KEYNOTE-942 ongoing clinical trial ( NCT03897881 ) compares the effectiveness of treatment of patients with stage
Risk-based breast cancer screening may be more efficient than age-based guidelines
Individually-tailored risk-based screening may be a more efficient way to screen for breast cancer. Image credit – National Cancer Institute CANCER DIGEST – Jan. 18, 2026 – Tailoring breast cancer screening to individual risk factors as opposed to relying on age guidelines may be a better way to reduce the chance of advanced cancer at diagnosis, a major screening study shows. The WISDOM study enrolled 46,000 women from all 50 states between 2016 and 2023. The aim was to compa
Durvalumab boosts survival for small-cell lung cancer but at a high cost
A new cost/benefit analysis of an immunotherapy drug that showed significantly longer survival for people with an aggressive form of lung cancer, called small-cell lung cancer, concludes that the treatment might be too expensive to be worth it.
Short bouts of intensive exercise may help with colorectal cancer treatment
Short intensive periods of physical activity can unleash several molecules in the blood linked to reducing inflammation and improving blood vessel function and metabolism, which can slow colorectal cancer growth.
Advanced gene editing technique helps patients with previously untreatable form of leukemia
Alyssa Tapley was the first patient to undergo a new gene therapy called BE-CAR7 for her T-cell acute lymphoblastic leukemia, a previously untreatable form of cancer. She has been cancer-free for more than three years. (Image credit – University College of London) CANCER DIGEST – Dec. 27, 2025 – Using a more precise genetic editing technique researchers at the University College of Lindon, in the United Kingdom have developed an advanced form of CAR-T cell therapy that has el
Keytruda® cuts distant spread in a rare aggressive skin cancer
Patients with a rare skin cancer who received an immunotherapy drug after surgery had a 42 percent lower risk of the cancer spreading to other parts of the body.
